On Sunday, the Chicago Cubs will face off against the Arizona Diamondbacks at Chase Field, with the first pitch scheduled for 4:10 p.m. ET. The Diamondbacks enter as -120 moneyline favorites, and the total runs for the game is set at nine.
Last season, the Cubs and Diamondbacks met six times and evenly split the series. In their current matchup, the teams have already traded victories in the first two games. For a detailed Cubs vs. D-Backs prediction, continue reading and explore our MLB Predictions to enhance your betting strategy!
*Article published before the conclusion of Saturday night’s game.
About the Author: Mike Briggs
Cubs Seeking Momentum Early in the 2025 Season
Chicago (1-3 SU, 1-3 RL, and 2-1-1 ATS) is set to start left-hander Matthew Boyd. The 34-year-old had a record of 2-2 with a 2.72 ERA and 1.13 WHIP in his eight outings last season with Cleveland. Boyd faced Arizona last in 2023, where he struggled, allowing five runs over six hits, including two home runs during a five-inning outing.
The Cubs split their first two games against the Diamondbacks, securing a 10-6 victory on Opening Day but fell 8-1 on Friday. Management made significant offseason adjustments by acquiring star outfielder Kyle Tucker, experienced starter Matthew Boyd, and reliever Ryan Pressly. These moves have aimed to create a more competitive roster for a potential division title run in 2025.
Chicago Cubs Injury Report: RP Javier Assad (oblique) is currently on the 15-day injured list.
Diamondbacks Boast Strong Offense but Face Pitching Challenges
Arizona (1-1 SU, 1-1 RL, and 1-0-1 O/U) will start lefty Eduardo Rodriguez. The 31-year-old compiled a 3-4 record with a 5.04 ERA and 1.50 WHIP during ten games last season. His last encounter with the Cubs was back in 2017 when he was with the Red Sox.
After a respectable 2024 season with 89 wins, the Diamondbacks struggled to replicate their success from their 2023 World Series run. With the Los Angeles Dodgers leading the National League West and other teams like the San Diego Padres and San Francisco Giants remaining competitive, the division is as tough as ever. Arizona led Major League Baseball in runs scored last season, yet faced difficulties with their pitching, ranking 27th in ERA at 4.62. To address this, they signed veteran righty Corbin Burnes to strengthen their rotation, especially after losing Jordan Montgomery for the season due to Tommy John surgery.
Arizona Diamondbacks Injury Report: No injuries to report for Thursday’s game against Chicago.
Smart Betting Choices for Cubs vs. Diamondbacks
Which team will claim victory in this exciting MLB matchup? Keep reading for insights into our Cubs vs. Diamondbacks prediction!
Looking for More Insights?
For additional analysis on this game, check out Chicago Cubs vs. Arizona Diamondbacks Prediction from Statsalt, our partner site.
